Renal Dialysis Clinical Trial
Official title:
Effect of Levamisole Supplementation on Tetanus Vaccination Response Rates in Hemodialysis Patients: A Randomized Double-Blind Placebo-Controlled Trial
Levamisole as an immunomodulator drug has been demonstrated to improve the immune response to Hepatitis B virus (HBV) vaccination in hemodialysis patients. The aim of this study was to evaluate the effect of levamisole supplementation on tetanus-diphtheria (Td) vaccine response rate in hemodialysis patients.
Levamisole as an immunomodulator drug has been demonstrated to improve the immune response to HBV vaccination in hemodialysis patients. The aim of this study was to evaluate the effect of levamisole supplementation on Td vaccine response rate in hemodialysis patients. In this randomized double-blind placebo-controlled trial 40 hemodialysis patients who had not received tetanus vaccination in a year before investigation and had unprotective anti-tetanus immunoglobulin G (IgG) levels (<0.1 International Unit [IU]/ml) were enrolled. These patients were randomized into two equal groups to receive one dose of intramuscular Td vaccine supplemented with either levamisole 100 mg or placebo daily, six days before and six days after vaccination. The anti-tetanus IgG levels were measured 1 and 6 months after vaccination. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05189795 -
The Construction of Physical ACtivity Enhancement Scheme (PACES) in Hemodialysis Patients
|
||
| Completed |
NCT01125202 -
Intervention to Reduce Dietary Sodium in Hemodialysis
|
N/A | |
| Completed |
NCT00806130 -
Health Related Quality of Life and Cognitive Function Among Norwegian Dialysis Patients
|
||
| Completed |
NCT00730145 -
A Single Dose Study Investigating The Elimination Of PD-0332334 In Patients Receiving Regular Hemodialysis
|
Phase 1 | |
| Completed |
NCT00753116 -
Renal Denervation in End Stage Renal Disease Patients With Refractory Hypertension
|
Phase 1 | |
| Completed |
NCT05718765 -
The Effect of Physical ACtivity Enhancement Scheme (PACES) in Hemodialysis Patients
|
N/A | |
| Completed |
NCT03250715 -
Effects of Low Level Laser Therapy on Functional Capacity and DNA Damage of Patients With Chronic Kidney Failure
|
N/A | |
| Completed |
NCT05469620 -
Adaptive Nutrition Therapy in Hemodialysis
|
N/A | |
| Completed |
NCT03536858 -
Social Networks and Renal Education: Promoting Transplantation
|
N/A | |
| Completed |
NCT00824837 -
Study of beta2-Microglobulin Removal by Standard Versus New High Cut-Off Haemodialysis Membrane
|
Phase 1/Phase 2 | |
| Completed |
NCT03403491 -
Study of Self-monitoring of Weight & Blood Pressure (Via patientMpower Platform) in Hemodialysis
|
N/A | |
| Terminated |
NCT02495662 -
The LIPMAT Study: Liposomal Prednisolone to Improve Hemodialysis Fistula Maturation
|
Phase 2 | |
| Completed |
NCT01179620 -
Certoparin in Renal Patients Undergoing Hemodialysis
|
Phase 3 | |
| Completed |
NCT01017276 -
A Phase 3 Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Peritoneal Dialysis
|
Phase 3 | |
| Active, not recruiting |
NCT04466865 -
A Communication Tool to Assist Older Adults Facing Dialysis Choices
|
N/A | |
| Recruiting |
NCT03782519 -
Quality of Life of Frail Aged Patients in Incremental Hemodialysis
|
N/A | |
| Recruiting |
NCT02843334 -
Study of the Prevalence of Fabry Disease in French Dialysis Patients
|
N/A | |
| Recruiting |
NCT02545530 -
Transdermal Clonidine in Chronic Hemodialysis Patients
|
N/A | |
| Completed |
NCT00892749 -
Long-term Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis
|
Phase 3 | |
| Completed |
NCT00649298 -
A Clinical Trial of IntensiVE Dialysis
|
Phase 4 |