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Clinical Trial Summary

This is a Phase Ib/II, open-label, single arm trial to evaluate the efficacy and safety of AK104 in combination with axitinib as a first-line treatment for advanced/metastatic special pathological subtypes of renal cell carcinoma (ssRCC). Subjects will receive AK104 plus axitinib until disease progression, development of unacceptable toxic effects, death, a decision by the physician or patient to withdraw from the trial. The primary endpoint is ORR and PFS per RECIST v1.1 and imRECIST as assessed by investigators.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05808608
Study type Interventional
Source West China Hospital
Contact Hao Zeng, Professor
Phone 8618980602129
Email kucaizeng@163.com
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date September 2023
Completion date December 2025

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