Renal Carcinoma Clinical Trial
Official title:
Robot-Assisted Laparoscopic HIFU (High-Intensity Focused Ultrasound) for Thermal Ablative Therapy of Small Renal Mass: Corroborating With Robot-Assisted Laparoscopic Partial Nephrectomy Specimens
This clinical trial studies a type of ultrasound called robot-assisted laparoscopic high-intensity focused ultrasound for performing thermal ablative therapy, or sound wave therapy, in treating patients with small kidney masses undergoing partial removal of the kidney. The robot-assisted ultrasound probe takes images of the kidney to help doctors locate the mass. The probe then uses high frequency sound waves to target and ablate (or destroy) the kidney mass, which may be a cancerous tumor or benign tissue. Surgery is then performed to remove the part of the kidney with the mass. Robot-assisted laparoscopic high-intensity focused ultrasound for thermal ablative therapy may be safer and help doctors see the tumor better when performing kidney surgery.
PRIMARY OBJECTIVES:
I. To evaluate the efficacy of laparoscopic high-intensity focused ultrasound (HIFU) for the
treatment of localized primary renal cancer to evaluate histological accuracy in successful
ablation of the small renal mass, matched with intraoperative targeting.
SECONDARY OBJECTIVES:
I. To evaluate the safety and toxicity of laparoscopic HIFU for patients with primary renal
cancer.
II. To evaluate the technical success of laparoscopic HIFU ablation.
OUTLINE:
Patients undergo robot-assisted laparoscopic HIFU thermal ablative therapy during partial
nephrectomy.
After completion of study treatment, patients are followed up at 2 days, 2 weeks, 1 month, 6
months, 12 months, and then annually for up to 3 years.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04718584 -
the Efficacy and Safety of LDP in Patients With Urinary and Male Genital Tumors
|
Phase 2 | |
Recruiting |
NCT03114826 -
Study of the Impact of VEGF Polymorphism on the Development of Renal Carcinoma in Renal Transplant Patients
|
N/A | |
Recruiting |
NCT02928692 -
Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium
|
Phase 3 | |
Recruiting |
NCT03475953 -
A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors
|
Phase 1/Phase 2 | |
Recruiting |
NCT03638206 -
Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies
|
Phase 1/Phase 2 | |
Recruiting |
NCT03786796 -
Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations
|
Phase 2 | |
Completed |
NCT03064308 -
The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery
|
N/A | |
Not yet recruiting |
NCT06318871 -
Memory-like Natural Killer (NK) Cell Therapy With N-803 in Patients With Renal Cell Carcinoma or Urothelial Carcinoma
|
Early Phase 1 | |
Not yet recruiting |
NCT05456074 -
Integrative Molecular Characterization Of MiT Family Translocation Renal Cell Carcinomas (IMCOR)
|
||
Recruiting |
NCT06290427 -
Comparison of Outcomes of Multiple Platforms for Assisted Robotic-Kidney (COMPAR-K)
|
N/A | |
Recruiting |
NCT04773951 -
A Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of JS004 in Advanced Solid Tumors
|
Phase 1 |