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Renal Artery Stenosis clinical trials

View clinical trials related to Renal Artery Stenosis.

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NCT ID: NCT00885768 Completed - Clinical trials for Renal Artery Stenosis

Prevalence of Renal Artery Stenosis in Patients Referred for Cardiac Catheterization

RAS
Start date: July 2008
Phase: Phase 3
Study type: Observational

All patients referred for coronary angiography will simultaneously be evaluated for renal artery stenosis and then stenosis more than 50% will be analyzed according to clinical conditions, risk factors and lab data.

NCT ID: NCT00845702 Terminated - Clinical trials for Renal Artery Stenosis

Renal Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF)

Start date: April 2009
Phase: Phase 3
Study type: Interventional

The study will evaluate the efficacy and safety of Dotarem enhanced MRA compared to TOF MRA in patients suffering from renal arterial disease.

NCT ID: NCT00714142 Completed - Renal Failure Clinical Trials

Renal Blood Flow Measurement With Positron Emission Tomography (PET)

Start date: August 2008
Phase: Phase 2
Study type: Interventional

Two investigational chemical tracers, 62Cu-ethylglyoxal bis(thiosemicarbazone) (62Cu-ETS) and 15O-water, will be used in this study to look at how blood moves through the kidneys. The purpose of the study is to see if 62Cu-ETS is effective in showing the blood supply to the kidneys compared to 15O-water. The tracer mixes with the blood and moves through the body. Using positron emission tomography (PET scan) the researchers can see the tracer and can learn more about how the blood moves through the kidneys. The study invites participants who are healthy, without any heart or kidney disease, patients who have kidney disease that require dialysis, and patients who may have a blockage in one of the arteries supplying blood to the kidneys.

NCT ID: NCT00711984 Recruiting - Clinical trials for Renal Artery Stenosis

Comparison of Stenting Versus Best Medical Therapy for Treatment of Ostial Renal Artery Stenosis: a Trial in Patients With Advanced Atherosclerosis

Start date: February 2004
Phase: Phase 4
Study type: Interventional

Renal artery stenosis (RAS) usually refers to a disease of the large extra-renal arterial vessels and most frequently is caused by atherosclerotic obstructions. The prevalence of atherosclerotic RAS increases with age, male gender, traditional cardiovascular risk factors (hypertension, diabetes, smoking, hyperlipidemia) and atherosclerotic comorbidities like coronary artery or peripheral artery disease (PAD). A prevalence up to 40% has been reported in patients with PAD. Undoubtedly, atherosclerotic RAS is a progressive disease, as more than half of the patients exhibit an increasing degree of stenosis within five years after diagnosis, and one out of five patients with a critical stenosis (>60%) suffers renal atrophy and renal failure during this period. RAS may be treated conservatively by so called best medical treatment, surgically, or by endovascular interventions using balloon angioplasty and stenting. The purpose of the investigators study is to determine the incidence and the predictors of RAS in patients with PAD, and to compare the effect of renal artery stenting versus best medical treatment in patients with hypertension and ostial renal artery stenosis in a randomized controlled trial.

NCT ID: NCT00640406 Completed - Clinical trials for Renal Artery Stenosis

Comparison of Best Medical Treatment Versus Best Medical Treatment Plus Renal Artery Stenting

RADAR
Start date: April 2008
Phase: Phase 3
Study type: Interventional

The clinical investigation is a prospective, international, multi-centre, randomized (1:1) trial with follow ups at 2, 6, 12 months and 3 years. The purpose of the study is to evaluate the clinical impact of percutaneous transluminal renal artery stenting (PTRAS) on the impaired renal function measured by the estimated Glomerular Filtration Rate (eGFR) in patients with hemodynamically significant atherosclerotic renal artery stenosis (ARAS).

NCT ID: NCT00631540 Completed - Clinical trials for Renal Artery Stenosis

REFORM Clinical Study: Treatment of Renal Artery Stenosis With the Formula Balloon-Expandable Stent

Start date: February 2008
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the safety and effectiveness of the Formula Balloon-Expandable Stent in treatment of renal artery stenosis.

NCT ID: NCT00310557 Completed - Clinical trials for Renal Artery Stenosis

Magnevist® Injection-enhanced MRA Compared to Non Contrast MRA for the Detection of Stenosis of the Renal Arteries

Start date: December 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to look at the safety (what are the side effects) and efficacy (how well does it work) of Magnevist (the study drug) used for MRI of the renal arteries. The results will be compared to the results of MRI taken without Magnevist and with the results of your X-ray angiography.

NCT ID: NCT00235157 Completed - Clinical trials for Renal Artery Stenosis

A Comparison of Coated and Uncoated Stents in Renal Artery Treatment.

GREAT
Start date: November 2001
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to compare the safety and performance of the Palmaz Genesis™ balloon expandable stent, with or without sirolimus coating in the treatment of renal artery stenosis, measured at 6 months follow up via angiography.

NCT ID: NCT00234585 Completed - Clinical trials for Renal Artery Stenosis

Prospective Randomized Study Comparing Renal Artery Stenting (RESIST)With/Without Distal Protection

Start date: August 2002
Phase: Phase 2
Study type: Interventional

This study is designed to demonstrate the safety and efficacy of using a protective device/drug to prevent renal injury during renal artery stenting and to assess whether the preventative effects are measurable and if there is a differential treatment effect for either device alone or in combination.

NCT ID: NCT00209391 Completed - Clinical trials for Renal Artery Stenosis

A Safety & Efficacy Clinical Study to Evaluate the Narrowing of the Renal Arteries While Using Gadodiamide

Start date: September 2003
Phase: Phase 3
Study type: Interventional

Magnetic Resonance Angiography (MRA) is an examination similar to Magnetic Resonance Imaging (MRI) which uses a magnetic field and a contrast medium when needed to visualize blood flow in the arterial vessels throughout the body. Gadodiamide, a contrast medium, is already approved and is used to image blood vessels by directly injecting it into the vein, but this procedure has not been formally tested to image the renal artery vessels using MR. The study is designed to determine the presence or absence of a relevant stenosis (ie greater than/equal to 50%) or occlusion in renal arteries. Intra-arterial Digital Subtraction Angiography will be used as the standard of truth.