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Clinical Trial Summary

This study is intended to evaluate efficacy and safety of targeted precision therapy in patients with refractory tumor, including rare tumor without standard recommended treatment and common tumor after multiple line of therapy.


Clinical Trial Description

The individuals recruited in the present study are with solid tumor, mainly including two parts: first, rare tumor without standard recommended treatment such as atypical fibrous histiocytoma; second, common tumor after multiple line of therapy such as lung cancer, gastric cancer, colorectal cancer, etc. All patients have no any standard therapy based on NCCN guideline when recruiting. Next-generation sequence was used to detect druggable molecular event including gene mutation, gene fusion, amplification, etc. Then patients with molecular events were treated with corresponding targeted drug and followed-up, and not limited tumor type. PD-1/L1 inhibior plus anti-angiogenic agent was used in patients without durgguable targets. The efficacy and safety of these regimens were evaluated. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03239015
Study type Interventional
Source Shanghai Changzheng Hospital
Contact Xiao-dong Jiao, MD.PHD
Phone +86-13817797639
Email pulava@163.com
Status Recruiting
Phase Phase 2
Start date January 1, 2017
Completion date December 31, 2023

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