Proton Beam Re-Irradiation in Thoracic Cancers

Recurrent Disease Clinical Trial

Official title: Definitive Re-irradiation With Proton Beam Radiotherapy for Patients With Recurrent Thoracic Cancers

Status Completed

Clinical Trial Summary

This pilot clinical trial studies proton beam radiation therapy in treating patients with thoracic cancer that has come back and have received prior radiation therapy. Proton beam radiation therapy uses high energy protons to kill tumor cells and may cause less damage to normal tissue.

Clinical Trial Description

PRIMARY OBJECTIVES:

I. To assess the grade 3 toxicity associated with thoracic re-irradiation with proton therapy, with prospectively applied normal organ radiation dose limits.

SECONDARY OBJECTIVES:

I. To assess the efficacy of thoracic re-irradiation with proton therapy.

OUTLINE:

Patients undergo proton beam radiation therapy per standard of care.

After completion of study treatment, patients are followed up at 3 months. ;

Related Conditions & MeSH terms

• Lung Neoplasms
• Metastatic Malignant Neoplasm in the Lung
• Neoplasms
• Neoplasms, Second Primary
• Recurrent Disease
• Thoracic Neoplasm
• Thoracic Neoplasms

• NCT number: NCT02204761
• Study type: Interventional
• Source: University of Washington
• Status: Completed
• Phase: N/A
• Start date: September 9, 2014
• Completion date: September 7, 2017