Umbilical Cord Serum Eye Drops

Recurrent Corneal Erosion Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01016158
• Other study ID #: I-2009-11-135
• Status: Completed
• Phase: N/A
• First received: November 18, 2009
• Last updated: November 18, 2009
• Start date: April 2006
• Est. completion date: October 2009

Study information

• Verified date: November 2009
• Source: Chonnam National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Korea: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

In the present study, the investigators investigated the efficacy of umbilical cord serum eye drops for the treatment of patients with recurrent corneal erosions. Group A were treated with 20% umbilical cord serum eye drops 3 to 4 times a day in addition to artificial tears, and group B were treated with artificial tears only. Ophthalmic examinations including visual acuity measurement and slit lamp biomicroscopy were performed before and every month after treatment. Recurrence was defined as the presence of clinical symptoms accompanied by epithelial defects in the cornea.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: October 2009
• Est. primary completion date: April 2009
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• patients with recurrent corneal erosions

Exclusion Criteria:

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Recurrent Corneal Erosion

Intervention

Drug:
• Umbilical cord serum eyedrops
20% umbilical cord serum eye drops 3 to 4 times a day

Locations

Country	Name	City	State
Korea, Republic of	Chonnam National University Hospital	Gwang-Ju

Sponsors (1)

Lead Sponsor	Collaborator
Chonnam National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

References & Publications (3)

del Castillo JM, de la Casa JM, Sardiña RC, Fernández RM, Feijoo JG, Gómez AC, Rodero MM, Sánchez JG. Treatment of recurrent corneal erosions using autologous serum. Cornea. 2002 Nov;21(8):781-3. — View Citation

Yoon KC, Im SK, Park YG, Jung YD, Yang SY, Choi J. Application of umbilical cord serum eyedrops for the treatment of dry eye syndrome. Cornea. 2006 Apr;25(3):268-72. — View Citation

Yoon KC, You IC, Im SK, Jeong TS, Park YG, Choi J. Application of umbilical cord serum eyedrops for the treatment of neurotrophic keratitis. Ophthalmology. 2007 Sep;114(9):1637-42. Epub 2007 Mar 26. — View Citation