Rectum Neoplasms Clinical Trial
Official title:
Multicenter Study on Outcomes and Protection of Urinary and Sexual Function of Laparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients
TME (Total mesorectum excision) is the golden standard of radical resection for mid-low
rectal cancer. However, the damage of pelvic autonomic nerve following with TME principle
will lead to high incidence of urinary and sexual function disorder. Open PANP (pelvic
autonomic nerve preservation) TME surgery played a role in decreasing incidence of urinary
and sexual function disorder. However, 32%-44% patients still suffered from urinary and
sexual function disorder when underwent Open PANP TME surgery (O-PANP-TME).
Laparoscopy-assisted TME surgery (L-TME) is applied wildly nowadays. In the early stage of
work, we performed laparoscopy-assisted PANP TME surgery (L-PANP-TME) to discuss the
protection of urinary and sexual function of male mid-low rectal cancer patients. The results
showed that L-PANP-TME significantly decreased incidence of urinary and sexual function
disorder. In order to further confirm our early work, we design a multiple-center randomized
controlled clinical trial to compare differences in urinary and sexual function protection
and long-term outcomes between L-PANP-TME and O-PANP-TME.
n/a
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