Rectum Neoplasms Clinical Trial
Official title:
Comparisons of Urinary and Sexual Function Protection and Long-term Outcomes Between Laparoscopy-assisted and Open Pelvic Autonomic Nerve Preservation Total Mesorectum Excision for Male Mid-low Rectal Cancer Patients: a Randomized Controlled Clinical Trial
TME (Total mesorectum excision) is the golden standard of radical resection for mid-low
rectal cancer. However, the damage of pelvic autonomic nerve following with TME principle
will lead to high incidence of urinary and sexual function disorder. Open PANP (pelvic
autonomic nerve preservation) TME surgery played a role in decreasing incidence of urinary
and sexual function disorder. However, 32%-44% patients still suffered from urinary and
sexual function disorder when underwent Open PANP TME surgery (O-PANP-TME).
Laparoscopy-assisted TME surgery (L-TME) is applied wildly nowadays. In the early stage of
work, we performed laparoscopy-assisted PANP TME surgery (L-PANP-TME) to discuss the
protection of urinary and sexual function of male mid-low rectal cancer patients. The results
showed that L-PANP-TME significantly decreased incidence of urinary and sexual function
disorder. In order to further confirm our early work, we design a randomized controlled
clinical trial to compare differences in urinary and sexual function protection and long-term
outcomes between L-PANP-TME and O-PANP-TME.
n/a
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