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Prediction Model for Lateral Lymph Node Metastasis

Rectal Cancer Clinical Trial

Official title:
Radiomics-based Prediction Model for Lateral Lymph Node Metastasis in Rectal Cancer

Clinical Trial Summary

Mid to low-lying rectal cancer patient with enlarged lateral lymph node befor treatment and receiving lateral lymph node dissection would be enrolled. Radiomics parameters of lateral lymph nodes would be extracted by expert software. Then a part of the nodes would be used as the training set to build the prediction model, and the another part nodes would be used as the validation set.

Clinical Trial Description

After performing lateral lymph node dissection for the enrolled patients, we would find the targeted lateral node which was matched with the enlarged one in imaging from the specimen. Then the nodes would be send for pathological examination. Then we would extract the radiomics parameters of the nodes from the pretreatment CT and MRI with ITK-SNAP software. According to the pathological status, lymph nodes and corresponding radiomics parameters would be divided into positive and negative groups. Then significant parameters would be selected by R software. Then the prediction model with nomogram would be developed. 70% nodes would be used for for model development and the other 30% would be used for validation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04635488
Study type Observational
Source West China Hospital
Contact Ziqiang Wang, MD
Phone 18980602028
Email wangziqiang@scu.edu.cn
Status Recruiting
Phase
Start date January 1, 2020
Completion date December 31, 2022
View Details
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