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Clinical Trial Summary

The purpose of the research is to evaluate whether both chemotherapy and radiotherapy can lead to higher rates of clinical complete response leading to organ preservation in human subjects with cancer. The objective is to learn if this treatment approach may safely be used as an alternative to the standard treatment for rectal cancer and to know the quality-of-life in these patients.


Clinical Trial Description

Primary Objective: To assess clinical complete response of an organ preservation approach using short course radiation followed by intensified chemotherapy. Secondary Objective: To assess safety in all enrolled patients, local regrowth rate and other cancer specific outcomes (metastasis-free survival, colostomy-free survival and overall survival), longitudinal health-related quality of life of this organ preservation approach ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04380337
Study type Interventional
Source Stanford University
Contact
Status Active, not recruiting
Phase Phase 2
Start date May 21, 2020
Completion date January 17, 2026

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