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Watch and Wait Management on Rectal Cancer Patients Using New Swift Local Therapy — Whistle  

Rectal Cancer Clinical Trial

Official title:
A Pilot Study of Dose-escalation Strategy of Radiotherapy Followed by Endorectal Brachytherapy With the Use of a New Rectal Applicator in Inoperable, Ederly Rectal Cancer Patients

Clinical Trial Summary

Within our institution, the principal investigator have acquired expertise in endorectal brachytherapy, a localized treatment for colorectal cancer. Until now a modality which uses an endorectal applicator has been used, which has certain limitations. In the context of this study, a new applicator will be used which is already approved by Health Canada for endorectal brachytherapy, thereby improving the participant's quality of life and optimizing treatment time.

Clinical Trial Description

The main goal of this study is to treat patients using external beam radiotherapy followed by endorectal brachytherapy using a new applicator. Validating the feasibility of this new applicator, assessing the treatment time required when using it, the necessary workload required and ultimately avoid the need for surgery are our main priorities. Currently, this option is still experimental, although several patients have been treated with this method during the last ten years. In this pilot study, 45 patients will be recruited, whom have medical conditions (co-morbidities) that make surgery very difficult, or patients that are refusing surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04336202
Study type Interventional
Source Sir Mortimer B. Davis - Jewish General Hospital
Contact Te Vuong, MD
Phone 514-340-8288
Email tvuong@jgh.mcgill.ca
Status Recruiting
Phase N/A
Start date August 2024
Completion date January 2028
View Details
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