Rectal Cancer Clinical Trial
Official title:
A Prospective Observational Study of Patients With Rectal Cancer After Concomitant Radiation and Chemotherapy
The purpose of this study is to investigate if operation and permanent stoma can be omitted in patients with cancer in the lower part of the rectum.
Patients entering this study are offered the possibility of avoiding an extensive operation
and a permanent stoma.
Over the past 2 years Vejle Hospital examined patients with rectal cancer during their course
of treatment and we have developed a method to predict complete response.
Patients in this study are treated with chemotherapy and external irradiation supplemented
with an endorectal boost (2 fractions). At the start of treatment and weeks 2, 4, and 6 of
the treatment course an endoscopy is performed to evaluate the response. The final evaluation
is performed 6 weeks after end of treatment. Patients with complete remission are offered
observation. Patients with residual tumor are advised to be operated.
Follow-up is performed every 2 months the first year and every 3 months the second year. 2
follow-up visits are planned for the third year. A yearly follow-up is scheduled for the
fourth and fifth year.
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