Rectal Cancer Clinical Trial
Official title:
Prevention of Acute Voiding Difficulty After Radical Proctectomy for Rectal Cancer With Tamsulosin
Various adrenergic blockers are used for acute voiding difficulty after proctectomy.
Recently, a selective alpha5-adrenergic blocker, Tamsulosin has been reported to have
benefit in reducing urinary symptom score and in reducing the rate of intermittent
self-catheterization for patients with rectal cancer after radical proctectomy.
This study is to evaluate the efficacy of pharmacologic prevention to ameliorate the
incidence of postoperative urinary dysfunction.
Acute voiding difficulty is caused from damage to pelvic sympathetic nerve after rectal
surgery, and usually resolved spontaneously within several months after the surgery.
However, acute voiding difficulty results in prolonged insertion of urinary catheter and is
associated risk for urinary tract infection. Various adrenergic blockers are used for acute
voiding difficulty after proctectomy. Recently, a selective alpha5-adrenergic blocker,
Tamsulosin has been reported to have benefit in reducing urinary symptom score and in
reducing the rate of intermittent self-catheterization for patients with rectal cancer after
radical proctectomy.
This study is to evaluate the efficacy of pharmacologic prevention to ameliorate teh
incidence of postoperative urinary dysfunction.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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