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NCT ID: NCT02538211 Completed - Tetanus Clinical Trials

The Role of the Intestinal Microbiome in Enteric and Systemic Vaccine Immune Responses

Rota-biome
Start date: September 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate if the intestinal microbiota influences rotavirus vaccine immune responses in healthy adult volunteers.

NCT ID: NCT02220439 Completed - Clinical trials for Rotavirus Infections

Does the Fecal Microbiome Influence Rotarix Immunogenicity

Start date: September 2013
Phase: N/A
Study type: Observational

This is a proposal for a nested case‐control study within an ongoing rotavirus vaccine immunogenicity clinical trial Karachi, Pakistan. The primary study aim is to compare the fecal microbiota composition and diversity of infants who do (control) and do not (case) demonstrate immune seroconversion to rotavirus vaccination. The infants will be matched for vaccination dose, age and breast‐feeding practices.