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Clinical Trial Summary

The good standard antibiotic prophylaxis pre elective C S is cefazolin and this study will approve addition of azithromycin to cefazolin will reduce post CS infections more than cefazolin only.


Clinical Trial Description

Patiants and methods

Randomization:

Patients fulfilling the inclusion criteria will be randomized to two groups. Both two group will receive standard prophylaxis antibiotic CEFAZOLIN (zinol) (at a dose of 1 g) 2 hours preoperative.

Control Group:

This group will include 200women undergoing elective cs. In this group, patients will receive standard antibiotic prophylaxis CEFAZOLIN (at a dose of 1 g) and azithromycin (at a dose of 1g) 2 hours preoperative.

Study Group:

This group will include 200women undergoing elective cs. In this group, patients will receive only standard prophylaxis antibiotic(CEFAZOLIN)

Inclusion criteria:

- Gestational age of 37 0/7 weeks and greater

- Elective cesarean section

- Medicaly free pregnant women

Exclusion criteria:

- a known allergy to azithromycin

- obstetric complications

- azithromycin use within 7 days before randomization

- chorioamnionitis or other infection requiring postpartum antibiotic therapy

- Pre-gestational diabetes ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03502356
Study type Interventional
Source Ain Shams University
Contact mohamed 20 amar, md
Phone 01024706467
Email drmohamed145@gmil.com
Status Recruiting
Phase Phase 1/Phase 2
Start date April 20, 2018
Completion date August 20, 2018