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DAHANCA 33: Image Guided Dose-escalated Radiotherapy to Patients With Hypoxic HNSCC

Radiotherapy Clinical Trial

Official title:
DAHANCA 33: Functional Image Guided Dose-escalated Radiotherapy to Patients With Hypoxic Squamous Cell Carcinoma of the Head and Neck

Clinical Trial Summary

Aim: To improve curability of radiotherapy in HNSCC patients identified by hypoxic FAZA-PET scanning

Clinical Trial Description

Prospective phase II study aiming to improve the outcome in hypoxic resistent patients identified by FAZA-PET. Inclusion: Patients must fulfill the following: Positive hypoxic FAZA-PET Scanning (as described in DAHANCA 24 - see citation) Stage III-IV, Squamous cell carcinoma of the larynx, pharynx or oral cavity (HPVneg (oropharynx) Indication for hyperfractionated accelerated radiotherapy with concommitant cis-platin and nimorazole ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02976051
Study type Interventional
Source Danish Head and Neck Cancer Group
Contact Jens Overgaard, MD, DMSc
Phone +45 78462629
Email jens@oncology.au.dk
Status Recruiting
Phase Phase 2
Start date January 2017
Completion date December 2022
View Details
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