HFNC vs LFNC in Patients With AF Undergoing RFCA Under Deep Sedation.

Status Recruiting

Clinical Trial Summary

Oxygen supplementation through high flow nasal cannula (HFNC) may reduce the incidence of desaturation and hypoxemia during deep sedation at radiofrequency catheter ablation (RFCA procedures).This study is designed to test the hypothesis that the incidence of hypoxemia and desaturation in patients with atrial fibrillation undergoing RFCA under deep sedation, is less when using HFNC as compared to use of standard low flow nasal cannula (LFNC).

Clinical Trial Description

Desaturation may occur in patients under deep sedation which results in an elevated risk for perioperative adverse events including hypoxemia (1-3). The incidence of hypoxemia was 168 per 1000 in a general procedural sedation and analgesia population (4). The clinical significance of transient episodes of hypoxemia remains debatable. However, many peri-operative incidents are often short-term and limited in nature, but a number of them are a predictor to a serious complication with a permanent injury (5).This study investigates if high flow nasal cannula (HFNC) as compared to low flow nasal cannula (LFNC) will result in a lower incidence of intra-procedural oxygen desaturation and hypoxemia in patients with atrial fibrillation undergoing deep sedation for radiofrequency catheter ablation (RFCA). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04842253
Study type	Interventional
Source	Maastricht University Medical Center
Contact	Marloes C Homberg, MPA
Phone	0031-43-3876543
Email	marloes.homberg@mumc.nl
Status	Recruiting
Phase	N/A
Start date	January 4, 2022
Completion date	May 2025

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