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Radiodermatitis clinical trials

View clinical trials related to Radiodermatitis.

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NCT ID: NCT04992650 Enrolling by invitation - Clinical trials for Breast Reconstruction

Ultrasonic Perfusion Imaging in Post-mastectomy Irradiated Patients

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate post-mastectomy breast skin blood supply (perfusion) after radiation therapy, and before and after fat grafting to the breast(s).

NCT ID: NCT04067310 Enrolling by invitation - Radiodermatitis Clinical Trials

Study Using Spray Skin Protector Versus Conventional Treatment to Prevent Acute Radiodermatitis.

Start date: December 16, 2020
Phase: N/A
Study type: Interventional

This is a randomized, open-label, single-institution trial designed to evaluate the effectiveness of a spray skin protector in preventing moist desquamation caused by radiotherapy treatment. This technology, spray skin protection, depending on the manufacturer, is primarily intended to prevent or reduce contact dermatitis. However, this study will be evaluated for use in preventing moist desquamation caused by ionizing radiation. The comparing agent will be a moisturizer, agreed upon at the local Institution of the study for use in the prevention of radiodermatitis. As secondary objectives: describe adverse events, diarrhea, pain and pruritus. The study will be conducted at the radiotherapy outpatient clinic of the Cancer Hospital I (HCI) of National Cancer Institute (INCA) in Brazil.

NCT ID: NCT02289365 Enrolling by invitation - Radiodermatitis Clinical Trials

Orally Administrated JBM-TC4 Prevents Acute Radiodermatitis in Breast Cancer Patients

Start date: November 2014
Phase: Phase 2
Study type: Interventional

This trial is designed as a multicenter, double-blinded, randomized, placebo controlled study to assess the safety and efficacy of JBM-TC4 for the prevention and treatment of acute radiation-induced dermatitis in breast cancer patients receiving radiotherapy.

NCT ID: NCT02251392 Enrolling by invitation - Radiodermatitis Clinical Trials

Evaluation of Therapeutic Efficacy in Use of Chamomilla Gel, Chamomilla Infuse and Urea in Radiodermatitis

ChamomillaTH
Start date: August 2015
Phase: Phase 3
Study type: Interventional

This study aims to evaluate therapeutics interventions in radiodermatitis in patients with breast or head and neck cancer. The data collect is going to begin after determining the better dose in a dose-response curve that is being conduct now in the same institution. To evaluate the skin reaction will be applied scale of the Radiation Therapy Oncology Group (RTOG) - Acute Radiation Morbidity Scoring Criteria, Common Terminology Criteria for Adverse Events (CTCAE) and Radiation-Induced Skin Reaction Assessment Scale (RISRAS).

NCT ID: NCT01481818 Enrolling by invitation - Clinical trials for Epigallocatechin Gallate

Study of Topically Applied Green Tea Extract for Radio Dermatitis and Radiation Mucositis

Start date: September 2011
Phase: Phase 1/Phase 2
Study type: Interventional

Radiodermatitis and radiation mucositis were the most frequent side-effect during the course of radiotherapy, especially when concurrent chemoradiotherapy applied. Since reactive oxygen species formed upon radiation therapy play a central role in initiating and driving the detrimental signaling events, antioxidant supplementation is thought to provide a photoprotective effect against radiation. Green tea extract has been shown to have antioxidant and anti-inflammatory effects on various types of cells. To evaluate the safety and efficiency of green tea extract in the treatment of radio dermatitis and radiation mucositis, the investigators conducted this phase Ⅰ,II study using topical EGCG in cancer patients receiving radiotherapy or concurrent chemoradiotherapy .