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NCT00178347 Clinical Trial

Radiation Dosimetry in Teeth

Radiation Tolerance Clinical Trial

Official title:
Radiation Dosimetry in Teeth

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT00178347
Other study ID # URCC 11070
Secondary ID
Status Terminated
Phase N/A
First received September 12, 2005
Last updated May 15, 2009
Start date December 2004

Study information
Verified date May 2009
Source University of Rochester
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Observational

Clinical Trial Summary

Irradiation of any tissue creates changes in that tissue. Ionizing radiation imparts charges to the tissue as it interacts with tissue components, changing the tissue structure. The specific type of modification also depends to some extent upon the type of tissue irradiated. It has been shown that it is possible to read the tooth enamel irradiation record using techniques such as electron paramagnetic resonance (EPR), or electron spin resonance (ESR).

It is proposed to examine radiation responses in approximately one hundred (100) human teeth. This would include teeth free of, as well as those containing, amalgam (silver) restorations. For the first group, teeth that have already been collected (pre-existing pathological specimens) would be used. These teeth were surgical/pathological discards collected without identifiers by the dental providers.

Recruitment information / eligibility
Status Terminated
Enrollment 10
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- Discarded pathologic specimens (teeth)

Study Design

Time Perspective: Retrospective

Related Conditions & MeSH terms

Intervention

Radiation:
• Exposure to irradiation
Treatment for Cancer using Radiation -dose will be the standard of Care for the type of Cancer being treated

Locations
Country Name City State
United States University of Rochester, Dept. Radiation Oncology Rochester New York

Sponsors (1)
Lead Sponsor Collaborator
University of Rochester

Country where clinical trial is conducted

United States, 

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