Radiation Exposure Clinical Trial
Official title:
Effect of Radioiodine Therapy on Ovarian Reserve in Female Patients With Differentiated Thyroid Cancer
| Verified date | May 2020 |
| Source | Assiut University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
Thyroid carcinoma is the most common endocrine malignancy. Surgery is the standard therapeutic approach for patients with differentiated thyroid carcinoma (DTC), followed by radioiodine (RAI) therapy if indicated. For women with DTC, the effects of RAI therapy on gonadal and reproductive function are an important consideration. This study aimed to evaluate the effects of RAI therapy on ovarian function.
| Status | Not yet recruiting |
| Enrollment | 38 |
| Est. completion date | December 15, 2021 |
| Est. primary completion date | June 15, 2021 |
| Accepts healthy volunteers | No |
| Gender | Female |
| Age group | 15 Years to 45 Years |
| Eligibility |
Inclusion Criteria: - Female patient in childbearing period. - Female patient with differentiated thyroid carcinoma. - Underwent thyroidectomy. - Candidate for radioactive iodine therapy. Exclusion Criteria: - • Male patients. - Postmenopausal female patients. - Female patients with undifferentiated thyroid carcinoma. - Pregnant female patients. - Lactating female patients. |
| Country | Name | City | State |
|---|---|---|---|
| n/a | |||
| Lead Sponsor | Collaborator |
|---|---|
| Assiut University |
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Level of anti-Müllerian (AMH) hormone | Level of anti-Müllerian (AMH) hormone in female patients before and after radioactive iodine therapy. | 6 months |
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