Pulpitis Clinical Trial
Official title:
Pulpotomy Versus Root Canal Therapy to Treat Irreversible Pulpitis in Human Permanent Molars: A Multicenter Randomized Non-inferiority Trial.
The purpose of this study is to demonstrate non-inferiority of pulpotomy treatment (with new endodontic bio-materials) as a new treatment with one-visit root canal therapy as reference treatment in pain relief and clinical and radiographic success, for irreversible pulpitis of human permanent molar teeth.
In one visit RCT (Arm 1): The teeth were anesthetized, isolated and endodontic access and
instrumentation of all canals was done. Canal preparation was conducted using a step-back
technique. The working lengths were determined and confirmed by radiography. Sterile normal
saline solution was used for intra-canal irrigation. Root canals were obturated with
gutta-percha and sealer using lateral condensation technique. After placing a cotton pellet
in the pulp chamber, the access cavity was closed with Cavit.
In pulpotomy treatment with CEM/MTA (Arm 2): The teeth were anesthetized. Pulpotomy
procedure of removing inflamed pulp tissue to the stump level was done. Homeostasis was
achieved by irrigating the cavity with sterile normal saline and application of small pieces
of sterile cotton pellets. The pulpal wound was covered with an approximately 2-mm-thick
layer of MTA/CEM cement. Pulp chambers were then covered with a wet cotton pellet and sealed
with Cavit.
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