Clinical Trials Logo
  1. Home
  2. Pulmonary Infection
  3. NCT04583046

Effects of Iloprost on Pulmonary Oxygenation in Obese Patients During One-lung Ventilation

Pulmonary Infection Clinical Trial

Official title:
Effects of Iloprost on Pulmonary Oxygenation in Obese Patients During One-lung Ventilation

Clinical Trial Summary

One lung ventilation (OLV) is essential during thoracic surgery. During OLV, intrapulmonary shunt can be increased resulting hypoxemia. Although OLV technique had been advanced so far, hypoxemia during OLV reaches about 10% in spite of inspired oxygen fraction 100%. Iloprost is a prostaglandin analogue used for pulmonary hypertension, which can decrease pulmonary artery resistance by selectively dilating pulmonary artery. In this prospective, randomized, double blind study, the investigator is planning to investigate the effects of iloprost on respiratory physiology (intrapulmonary shunt, deadspace, oxygenation, etc) in obese patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04583046
Study type Interventional
Source Yonsei University
Contact Young Jun Oh
Phone +82-2-2228-2423
Email yjoh@yuhs.ac
Status Not yet recruiting
Phase N/A
Start date October 2020
Completion date August 2022
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT03687177 - Visual Cue as Prevention of Pulmonary Infection Under Mechanical Ventilation N/A
Completed NCT03995030 - Massively Parallel Sequencing to Identify Microbiological Organisms in Bronchoalveolar Lavage Fluid
Recruiting NCT05552872 - Study on Diagnosis Value of mNGS Technology Among Diabetic Patients With Pulmonary Infections
Recruiting NCT04624490 - Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease Phase 1
Recruiting NCT05505487 - Construction and Effect Evaluation of Integrated Care Model for Pulmonary Infection in Stroke Patients With Tracheotomy N/A
Terminated NCT04348513 - Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection Phase 2
Completed NCT03438383 - Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery N/A
Completed NCT03933878 - Rapid Detection of Airway Pathogens for Lung Transplantation
Completed NCT05844215 - MMP-9, TIMP-9 in Lung Imaging and Functional of COVID-19
Completed NCT02779595 - Change of Regional Ventilation During Spontaneous Breathing After Lung Surgery N/A
Recruiting NCT06368388 - Bacteriophage Therapy for Difficult-to-treat Infections: the Implementation of a Multidisciplinary Phage Task Force
Recruiting NCT04457609 - Administration of Allogenic UC-MSCs as Adjuvant Therapy for Critically-Ill COVID-19 Patients Phase 1
Completed NCT01525121 - Expiratory Rib Cage Compression in Mechanically Ventilated Patients N/A
Active, not recruiting NCT03617393 - Study on Appropriate Technology of Standardized Diagnosis and Treatment for Diabetic Patients With Pulmonary Infections
Completed NCT05226403 - COVID-19 : Pulmonary Ultrasound in Primary Care
Terminated NCT04422691 - Ultrasonography in Norwegian Emergency Department Patients With Suspected Covid-19 Infection
Completed NCT04553315 - the Effect of Chest Expansion Exercises on Pleural Effusion N/A
Recruiting NCT06282835 - Eravacycline Combination Therapy for MRAB
Completed NCT02419196 - Perioperative Change of Regional Ventilation During Spontaneous Breathing N/A
Completed NCT01058356 - Effect of Probiotic Lactobacilli (Lacidofil Cap®) for the Prevention of Antibiotic-Associated Diarrhea N/A