Pulmonary Atelectasis Clinical Trial
Official title:
Comparison Between Ventilator Hyperinflation and Manual Rib Cage Compression: Randomized Crossover Trial
Verified date | August 2018 |
Source | Brazilian Institute of Higher Education of Censa |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This is a randomized crossover trial to evaluate the effects of thoracic compression applied alone or in association with hyperinflation maneuver with the ventilator. In addition, the mobilized volume and peak expiratory flow resulting from both maneuvers will be evaluated.
Status | Completed |
Enrollment | 30 |
Est. completion date | July 11, 2017 |
Est. primary completion date | December 5, 2014 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 90 Years |
Eligibility |
Inclusion Criteria: - patients under mechanical ventilation - diagnosis of pulmonary infection - hypersecretive Exclusion Criteria: - haemodynamic instability (heart rate > 130 bpm and mean arterial pressure < 60 mmHg) - acute bronchospasm - acute respiratory distress syndrome - untreated pneumothorax |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Brazilian Institute of Higher Education of Censa |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Static compliance of respiratory system | Compliance was assessed through the occlusion maneuver at the end of inspiration, considering tidal volume, plateau pressure and PEEP. Three measurements were taken at each moment, the mean being used. | Baseline (before), immediately after ventilator hyperinflation or rib cage compression and five minutes after aspiration | |
Primary | Total Resistance of respiratory system | The total resistance of the respiratory system was evaluated through the occlusion maneuver at the end of the inspiration, considering the resistive pressure, measured by the difference between the maximum plateau pressure. Three measurements were taken at each moment, the mean being used. | Baseline (before), immediately after ventilator hyperinflation or rib cage compression and five minutes after aspiration | |
Primary | Airway Resistance | The airway resistance was assessed by means of the occlusion maneuver at the end of the inspiration, considering the rapid fall of the pressure immediately after the occlusion, measured by the difference between the maximum pressure and P1. Three measurements were taken at each moment, the mean being used. | Baseline (before), immediately after ventilator hyperinflation or rib cage compression and five minutes after aspiration | |
Primary | Peak expiratory flow | The peak expiratory flow was evaluated through passive expiration, being considered the greatest value of the flow in the expiratory phase. | Baseline (before), immediately after ventilator hyperinflation or rib cage compression and five minutes after aspiration |
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