Clinical Trials Logo

Clinical Trial Summary

Current World Health Organization guidelines recommend routine antibiotic prophylaxis for women with perineal tear 3rd and 4th degree but not for 2nd degree because of insufficient evidence of effectiveness. The investigators aimed to investigate whether antibiotic prophylaxis prevented maternal infection after the first and second perineal tear after vaginal birth.


Clinical Trial Description

The PATPET trial is a randomized, controlled trial done at tertiary hospital obstetric units in Israel. Women who had first and second-degree tear (or after episiotomy) after delivery at 37 weeks or greater gestation, with no indication for ongoing prescription of antibiotics in the post-partum period and no contraindications to prophylactic Cefamezin (cefazolin), were randomly assigned (1:1) to receive a single intravenous dose of prophylactic antibiotic or not. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04763486
Study type Interventional
Source Meir Medical Center
Contact Yair Daykan, Dr
Phone +972542198231
Email yair.dykan@gmail.com
Status Not yet recruiting
Phase N/A
Start date March 1, 2021
Completion date March 1, 2023

See also
  Status Clinical Trial Phase
Terminated NCT05603624 - Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term N/A
Recruiting NCT01039051 - Diet and Lifestyle Intervention Study in Postpartum Women in China Phase 2/Phase 3
Recruiting NCT03397615 - Effect of Vaginal Douching With Betadine Before CS for Prevention of Post Operative Infections N/A
Recruiting NCT00136370 - Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn Phase 3