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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT02911532
Other study ID # 20160816
Secondary ID
Status Recruiting
Phase N/A
First received August 26, 2016
Last updated August 12, 2017
Start date October 1, 2016
Est. completion date April 1, 2018

Study information

Verified date August 2017
Source Shandong Eye Hospital
Contact Suxia Li, researcher
Phone 8615854107085
Email ykyykjk@163.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to determine whether tissue engineering conjunctiva is effective in the treatment of pterygium and atretoblepharia.


Description:

The most important area for research on the pterygium are the recurrence occurred after operation. Now the best way to prevent the recurrence is autologous conjunctival stem cell transplantation, but this way of operation can cause lack of conjunctiva and conjunctival scar, even may effect the later glaucoma surgery. For the atretoblepharia patients, amniotic membrane transplantation and autologous oral mucosa transplantation can not make effect to alleviate it. In this pilot project, investigators would like to study the effect of tissue engineering conjunctiva transplantation in the treatment of pterygium and tissue engineering conjunctiva transplantation combined with conjunctiva sac formation for the treatment of atretoblepharia. This will allow us to determine if useful data can be obtained, and if so, lead to further studies in various conjunctiva loss caused by trauma, infections, and so on.


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Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
Tissue engineering conjunctiva transplantation
During the operation,transplant the tissue engineering conjunctiva to the conjunctiva loss position

Locations

Country Name City State
China Shandong Eye Hospital Jinan Shandong

Sponsors (1)

Lead Sponsor Collaborator
Shandong Eye Hospital

Country where clinical trial is conducted

China, 

References & Publications (13)

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Outcome

Type Measure Description Time frame Safety issue
Primary The epithelial defect size of the transplanted tissue engineering conjunctiva the 7 days after operation
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