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Clinical Trial Summary

The purpose of this study is to compared between conventional pterygium excision and AMT transplantation with suture and with fibrin glue.


Clinical Trial Description

There are few studies about use of fibrin glue in pterygium surgery with conjunctival auto-graft with promising outcome. Less recurrent rate, less discomfort and halve surgical time were reported.

Up to our knowledge,there is no report of fibrin glue in pterygium excision with amniotic membrane transplantation(AMT). There is conventional technique to use AMT in King Chulalongkorn Memorial Hospital because some benefits over conjunctival auto-graft e.g.

- Preserve healthy superior conjunctiva for future glaucoma filtering surgery

- Can use in big or 2-headed pterygium

- Not contract as conjunctival graft esp. in case of fibrin glue

- Potential easier to use with fibrin glue

- Available from Thai Red Cross Eye Bank Comparison(s): amniotic membrane transplantation using fibrin glue compare to suture after pterygium excision. ;


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00457223
Study type Interventional
Source Chulalongkorn University
Contact
Status Completed
Phase Phase 2/Phase 3
Start date April 2007
Completion date August 2007

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