Pulsed Dye Laser for the Psoriatic Nail

Psoriatic Nail Clinical Trial

Official title:

Pulsed Dye Laser for the Psoriatic Nail

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01303185
• Other study ID #: 99074
• Status: Completed
• Phase: N/A
• First received: February 22, 2011
• Last updated: December 11, 2014
• Start date: January 2011
• Est. completion date: February 2012

Study information

• Verified date: December 2014
• Source: Taipei Medical University WanFang Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Taiwan: Department of Health
• Study type: Observational

Clinical Trial Summary

The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.

Description:

Psoriatic nails of patient's right hand were treated using PDL (595 nm) .The pulsed duration is 1.5ms, the beam diameter is 7mm, and the laser energy is 8.0 to 10.0 J/cm2. The treatment course of pulse dye laser is once monthly for 6 months. Psoriatic nails of both hands are treated with Tazarotene cream for 6 months. Clinical efficacy is statistically evaluated according to Nail Psoriasis Severity Index (NAPSI) score differences between right and left hand one month after 3rd and 6th therapy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: February 2012
• Est. primary completion date: February 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 16 Years and older

Eligibility

Inclusion Criteria:

• Psoriatic nail refractory to other topical and systemic treatment therapy

• ? 16 years old

Exclusion Criteria:

• Patient with pregnancy

• Patient with photo sensitivity

• Patient with severe wound around finger nails or paronychia

• Patient with hypersensitivity to Tazarotene cream

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Psoriatic Nail

Locations

Country	Name	City	State
Taiwan	Taipei Medical University - WanFang Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
Taipei Medical University WanFang Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	NAPSI		3rd and 6th months	No
Primary	global physician assessment		3rd and 6th months	No