Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus

Status Recruiting

Clinical Trial Summary

To investigate the potential efficacy of dupilumab in the treatment of moderate to severe chronic hepatic pruritus.

Clinical Trial Description

This is a 22-week (2 week screening, 18-week treatment period followed by a 2 week followup), phase II, open label, exploratory study to investigate the potential efficacy of FDA approved dupilumab in the treatment of adults with moderate to severe chronic hepatic pruritus. Subjects will be screened at outpatient clinic visit appointments and interested qualified subjects will be consented and offered participation in this trial. Once consent has been obtained, baseline values will be established and subjects will begin treatment and follow-up for the next 20 weeks. A final visit will be needed for evaluation and questionnaire completion. ;

Study Design

Related Conditions & MeSH terms

Pruritus

Clinical Trial Details

NCT number	NCT04256759
Study type	Interventional
Source	Mayo Clinic
Contact	Rachel A Pung Page
Phone	904-953-8513
Email	White.Rachel2@mayo.edu
Status	Recruiting
Phase	Phase 2
Start date	September 1, 2020
Completion date	May 2025

View Details

See also
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