Pruritus Clinical Trial
Official title:
Frequency and Characteristics of Pruritus in Patients With Monoclonal Gammopathy
Pruritus is most often secondary to dermatitis but can also occur without skin lesions, it is
called pruritus sine materia. The causes of pruritus sine materia are various: haematological
(myeloproliferative neoplasia ...), hepatic (cholestasis ...), renal (chronic renal failure,
dialysis), endocrine (iron deficiency ...), secondary to drug intake ... or idiopathic when
no cause is found.
Gammapathies are among the causes of pruritus sine materia, and as such electrophoresis of
serum proteins is usually part of the pruritus assessment to look for monoclonal gammopathy
(MGUS, multiple myeloma, Waldenström disease). However, there is very little data on the
frequency of pruritus in patients with monoclonal gammopathy and the characteristics of this
pruritus. So the aim of this study is to compare the frequency of pruritus between patients
with monoclonal gammapathy and controls
n/a
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