Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis

Pruritus Clinical Trial

— PRURI-MUSIC  

Official title:

Randomized Prospective Open-label Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03701971
• Other study ID #: 29BRC18.0112
• Status: Completed
• Phase: N/A
• Start date: November 8, 2018
• Est. completion date: April 19, 2019

Study information

• Verified date: August 2019
• Source: University Hospital, Brest
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Many clinical studies have shown the benefit of music therapy in various pathologies, including pain, and it is now established that the latter has a complementary therapeutic interest. Its most frequently identified indications are the fight against acute or chronic pains, the reduction of anxiety, depression and stress, as well as memory disorders such as Alzheimer's disease.

The main modes of action of music therapy involve sensory, cognitive, psychological and behavioral processes that are also found in pruritus.

Pruritus is defined as "an uncomfortable sensation causing the need to scratch. It has similarities with pain but also differences: relief by heat / cold, scratching / withdrawal behavior, localization on the skin, semi-mucous / ubiquitous ... etc.

The pathophysiology also has similarities, pruritus is born at the dermal-epidermal junction at the level of specific cutaneous receptors then follows the classical pathways through a 1st neuron, then the dorsal horn of the spinal cord and a second neuron. At the cerebral level, there is no single center of pruritus but several motor and sensory areas involved.

The similarities suggest that music therapy may have an interest in the management of chronic pruritus, especially since classical treatments (antihistamines, topical corticosteroids) have only partial efficacy in some dermatoses

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: April 19, 2019
• Est. primary completion date: April 19, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• At least 18 years of age

• Patient with pruritic dermatosis whatever the etiology (psoriasis, atopic dermatitis, toxiderma, cutaneous lymphoma, chronic urticaria ...)

• Hospitalized in continuous hospitalization in the Dermatology Department

• Age of dermatosis = 1 month

• Pruritus score = 3/10 by numerical evaluation

• Patient having signed a consent form

Exclusion Criteria:

• Patient under the age of 18

• Major impairment of hearing function

• Presence of major cognitive disorders

• Refusal to participate

• Pregnant or lactating women

• Institutionalized or emergency patients

• Patient under legal protection regime

• Patient not affiliated to the social security system

Related Conditions & MeSH terms

• Dermatitis
• Pruritus

Intervention

Other:
• evaluation of the intensity of pruritus
evaluation of the intensity of pruritus with various questionnaires

Locations

Country	Name	City	State
France	Brest University Hospital	Brest

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Brest

Country where clinical trial is conducted

France, 

References & Publications (34)

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* Note: There are 34 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Variation in the intensity of pruritus	Variation in the intensity of pruritus on the digital scale of pruritus	Hour 0 / Hour 1
Secondary	To study the effect of music therapy on the patient's anxiety	Completion of questionnaire State-Trait Anxiety Inventory (STAI Y-A)	Hour 0 / Hour 1
Secondary	To study the effect of music therapy according to the etiology of pruritus	Completion of Questionnaire 5D itch scale	Hour 0
Secondary	To study the impact of pruritic dermatitis on the quality of life of the patient	Completion of Questionnaire Itchy Quality of Life	Hour 0
Secondary	To study the satisfaction of the patients concerning the music session	Completion of questionnaire PGIC (Patient's Global Impression of Change)	Hour 1