Protein Metabolism Clinical Trial
Official title:
Role of the Protein Matrix in the Anabolic Response to a Ground Beef Patty as Opposed to the Impossible (Vegi-) Burger
NCT number | NCT05197140 |
Other study ID # | 273554 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | May 1, 2022 |
Est. completion date | November 3, 2022 |
Verified date | March 2023 |
Source | University of Arkansas |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Several of the investigator's recent studies have shown that all dietary proteins are not equal when it comes to making proteins in human bodies. Generally, foods made from animal muscle tissue are much more efficient at making new proteins in the body that those from plant sources. This study will measure the amount of protein growth in participants after consuming either one beef patty, one vegi-burger, or two vegi-burgers. By using stable isotope infusions and collecting blood and leg muscle samples, the investigator's lab can determine the rate of muscle metabolism that happens after a participant eats a protein-containing food. The investigator wants to determine if the vegi-burger is as efficient as the beef patty at creating proteins in a participants. The investigator will measure this metabolism over a 10-hour period, with the food being eaten at the 4 hour mark. The investigator plans to perform this procedure on up to 8 participants per food option (24 total).
Status | Completed |
Enrollment | 33 |
Est. completion date | November 3, 2022 |
Est. primary completion date | November 3, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 40 Years |
Eligibility | Inclusion Criteria: - Ages 18 - 40 yrs. - Body Mass Index of 20-32 inclusive Exclusion Criteria: - Unwilling to eat animal proteins - History of diabetes that requires medication for control of blood glucose - History of malignancy or chemo/radiation therapy in the 6 months prior to enrollment - History of gastrointestinal bypass/reduction surgery (Lapband, gastric sleeve, etc.) - Pregnant females - Hemoglobin less than 12 g/dL at screening - Platelets less than 150,000 at screening - Subjects who cannot refrain from using protein or amino acid supplements for 7 days prior to Visit 3 - Concomitant use of oral or injectable corticosteroids - Concomitant use of testosterone, IGF-1, or similar anabolic agent - Any other disease or condition that would place the subject at increased risk of harm if they were to participate, at the discretion of the study physician |
Country | Name | City | State |
---|---|---|---|
United States | UAMS Center on Aging | Little Rock | Arkansas |
Lead Sponsor | Collaborator |
---|---|
University of Arkansas |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Plasma amino acid concentrations (area under the curve after consumption of intervention/s) | 6 hours after consumption of intervention |
Status | Clinical Trial | Phase | |
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Completed |
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