Protein C Deficiency Clinical Trial
Official title:
Investigation of Ghrelin Levels in Patients With Protein C Deficiency
NCT number | NCT04180657 |
Other study ID # | 69965 |
Secondary ID | |
Status | Not yet recruiting |
Phase | |
First received | |
Last updated | |
Start date | January 2020 |
Est. completion date | July 2020 |
In rodents with protein C deficiency elevated levels of ghrelin has been observed. The
purpose of this study is to investigate if patients with protein C deficiency also have
elevated levels of ghrelin, and if so, how this affects the patients.
30 patients with protein C deficiency and 30 healthy BMI and gender matched controls are
recruited. Bloodsamples are taken in order to measure ghrelin and GH levels and other
metabolic parameters. The patients and controls are also asked to answer a questionaire
regarding appetite.
If patients with protein C deficiency have higher levels of ghrelin than the general
population, this will lead to new studies that will perhaps help us understand the importance
of ghrelin in humans.
Status | Not yet recruiting |
Enrollment | 60 |
Est. completion date | July 2020 |
Est. primary completion date | April 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - protein C deficiency or healthy subjects - age 18-70 - BMI 18-35 - written statement to join the study Exclusion Criteria: - chronic illness, apart from protein C deficiency and lifestyle diseases - everyday medication apart from statins, oral diabetes medication and antihypertensive drugs. - blood donation within three months prior to the investigation. - Alcohol abuse |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
University of Aarhus |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | acyl ghrelin and des acyl ghrelin measured in mg/dl | 6 month | ||
Secondary | Growth hormone measured in pmol/L | 6 month |
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