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Prostatic Hyperplasia clinical trials

View clinical trials related to Prostatic Hyperplasia.

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NCT ID: NCT02006303 Recruiting - Urinary Retention Clinical Trials

Prostatic Artery Embolization Versus 532 nm Green Light PVP for Catheterized Patients

Start date: December 2013
Phase: Phase 4
Study type: Interventional

The primary objective is to assess whether prostatic artery embolization has a similar efficacy and safety profile as GreenLight PVP in treating patients with urinary retention secondary to benign prostate hyperplasia (BPH). Subjects who consent will be randomized to either the Prostate embolization (PAE) arm or to the GreenLight PVP arm. The primary endpoint of efficacy of the procedure is measured by the ability of the patient to void. The secondary endpoints recorded will include patients' satisfaction measured by International Prostate Symptom Score (IPSS), peak flow rate (Qmax) and post-void residual urine volume (PVR) and prostate specific antigen (PSA) will be measured at 3, 6, and 12 months post treatment. Also, reduction in prostate volume is considered by MRI preoperatively, 3 months and 12 months.

NCT ID: NCT01967251 Withdrawn - Clinical trials for Erectile Dysfunction

Efficacy, Safety and Dose-response of Udenafil in Patients With Benign Prostatic Hyperplasia and Erectile Dysfunction

Start date: September 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy, dose-response and safety of udenafil 25 mg, 50 mg and 75 mg every day (q.d.) for 12 weeks in the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH and for the treatment of erectile dysfunction (ED).

NCT ID: NCT01966614 Completed - Clinical trials for Benign Prostatic Hyperplasia

Randomized, Double-Blind, Vehicle-Controlled, Multicenter Safety and Efficacy Study of Intraprostatic PRX302 for LUTS BPH

PLUS-1
Start date: October 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of a single treatment of PRX302 for the treatment of Benign Prostatic Hyperplasia (BPH) as compared to placebo.

NCT ID: NCT01963312 Completed - Clinical trials for Benign Prostatic Hyperplasia

Clinical Trial to Evaluate the Efficacy and Safety of the Transarterial Supraselective Embolization of the Prostate to Treat the Urinary Symptoms.

Start date: March 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the transarterial supraselective embolization (TSE) is a technique as effective as transurethral resection of the prostate (TURP) for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH).

NCT ID: NCT01958892 Completed - Clinical trials for Benign Prostatic Hyperplasia

To Compare Outcomes After Transurethral Enucleation of Prostate Versus Transurethral Resection of Prostate

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of the study is to assess whether transurethral enucleation of prostate gives better or equivalent outcomes compared to the gold standard of transurethral resection of the prostate

NCT ID: NCT01957189 Completed - Clinical trials for Prostatic Hyperplasia

This Will be an Open-label, Three-period, Fixed-sequence Study to Evaluate the Drug-drug Interaction, Pharmacokinetics and Safety of Dutasteride and Tamsulosin When Administered Alone and In-combination in Chinese Healthy Male Volunteers. The Study Will Last Approximately Eleven Weeks. Blood Samples

Start date: October 25, 2013
Phase: Phase 1
Study type: Interventional

This will be an open-label, three-period, fixed-sequence study to evaluate the drug-drug interaction, pharmacokinetics and safety of dutasteride and tamsulosin when administered alone and in-combination in Chinese healthy male volunteers.

NCT ID: NCT01952912 Completed - Clinical trials for Benign Prostate Hyperplasia

Plasmakinetic Enucleation of the Prostate and Open Prostatectomy to Treat Large Prostates

Start date: January 2004
Phase: N/A
Study type: Interventional

The investigators hypothesize that Plasmakinetic Enucleation of the Prostate (PkEP) might yield functional results comparable to OP but with lower perioperative morbidity, and have equivalent long-term efficacy with OP for large prostates. The first objective was to demonstrate the non-inferiority of PKEP compared to OP concerning Qmax at one year postoperatively. To explore the long-term efficacy, we compared the efficacy, safety, and morbidity of PkEP with those of OP in BPH patients with prostate glands larger than 100 g over a follow-up period of 6 years.

NCT ID: NCT01942551 Completed - Clinical trials for Benign Prostate Hyperplasia

Safety and Pharmacokinetic Interaction Study of Tadalafil and Dutasteride

Start date: September 2013
Phase: Phase 1
Study type: Interventional

This is an open-label, two-arm, one-sequence, cross-over study to evaluate the safety and pharmacokinetic interaction after oral concomitant administration of tadalafil and dutasteride in healthy male volunteers.

NCT ID: NCT01939184 Completed - Clinical trials for Benign Prostatic Hyperplasia

Assess Safety & Efficacy of WC3055 in Men With Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

Start date: August 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of various fixed daily doses of WC3055 compared with placebo for the treatment of subjects with LUTS secondary to BPH.

NCT ID: NCT01937871 Completed - Clinical trials for Erectile Dysfunction

A Study of Tadalafil in Men With Benign Prostatic Hyperplasia (BPH) and Erectile Dysfunction (ED)

Start date: September 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to see whether tadalafil can reduce the signs and symptoms in men with Erectile Dysfunction (ED) and Benign Prostatic Hyperplasia-Lower Urinary Tract Symptoms (BPH-LUTS) and improve their quality of life.