Propofol Clinical Trial
Official title:
Comparison of the Effect od Ketofol and Propofol on Intracranial Pressure Evaluated by Sonographic Optic Nerve Sheath Diameter Measurements in the Endoscopic Retrograde Cholangiopancreatography Procedures
Aim: To compare the effect of procedural anesthesia management with ketofol and propofol on the sonographic optic nerve sheath diameter in the endoscopic retrograde cholangiopancreatography (ERCP) procedures.
Adequate visualization of the gastrointestinal mucosa during endoscopic retrograde cholangiopancreatography (ERCP) requires distention of the intestinal lumen by gas insufflation. High intraluminal pressures can increase intraabdominal pressure, leading to an increase in intracranial pressure. Ultrasonographic measurement of the optic nerve sheath diameter is a simple, non-invasive, and reliable technique for assessing intracranial pressure. Propofol, a sedative-hypnotic agent with rapid onset and short duration of action, is often used.Theoretically, the combination of ketamine and propofol may maintain sedation efficacy while reducing cardiovascular side effects through dose reduction and due to its synergistic effects. The aim of this study is to demonstrate whether our anesthesia management has an effect on ICP change by measurement of optic nerve sheath diameter, predicting that insufflation performed for imaging during the ERCP procedure increase intraabdominal pressure, and frequently observed situations such as insufficient sedation, prone position, coughing and Valsalva during the procedure increase intracranial pressure (ICP). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04235894 -
An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia
|
||
| Completed |
NCT05103735 -
Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity
|
||
| Recruiting |
NCT06210061 -
Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring
|
N/A | |
| Completed |
NCT06098196 -
Effects of Aminophylline Bolus on TCI (Target Controlled Infusion) Concentrations at Return of Responsiveness
|
||
| Completed |
NCT06098209 -
Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress Marker
|
N/A | |
| Completed |
NCT04805775 -
Desflurane and Postoperative Sleep Quality in Patients Undergoing Elective Breast Surgery
|
N/A | |
| Recruiting |
NCT05971121 -
Comparing Ciprofol and Propofol for Sedation in Hypotensive ICU Patients: a Single Center Prospective Cohort Study
|
||
| Recruiting |
NCT05533580 -
Differential Effects of Remimazolam and Propofol on Dynamic Cerebral Autoregulation During General Anesthesia
|
N/A | |
| Recruiting |
NCT05533567 -
Electroencephalographic Profiles During General Anesthesia: a Comparative Study of Remimazolam and Propofol
|
N/A | |
| Completed |
NCT06243822 -
Ketamine Versus Propofol as ICU Sedation
|
Phase 4 | |
| Completed |
NCT03741361 -
The Impact of Anxiety or Depression on the Sedative Concentration of Propofol
|
||
| Recruiting |
NCT06403852 -
Investigating Near-Threshold Perception During Anesthetic Sedation
|
Phase 2 | |
| Not yet recruiting |
NCT06386965 -
Sevoflurane Versus Propofol: Effect on Stress Response
|
||
| Recruiting |
NCT02687568 -
Values of Enhanced Monitoring by EEG Recording (Narcotrend) for Sedation in Colonoscopy
|
N/A | |
| Completed |
NCT01941888 -
Propofol TCI Administered by Gastroenterologists During Endoscopy: a Randomized Double Blind Controlled Study
|
Phase 4 | |
| Completed |
NCT04123249 -
The Effects of Intravenous Anesthetics and Inhaled Anesthetics on Patients' Postoperative Sleep
|
N/A | |
| Recruiting |
NCT05352685 -
Effects of Propofol on Auditory Event-related Potentials and Brain Functional Connectivity in Patients With Supratentorial Glioma
|
N/A | |
| Completed |
NCT05800288 -
Effect of Midazolam Bolus on Eleveld and Schnider TCI (Target Controlled Infusion) Models
|
||
| Recruiting |
NCT04729478 -
Comparison Between Natural Sleep Endoscopy and Drug-induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea
|
N/A | |
| Completed |
NCT04394897 -
Total Intravenous Anesthesia With Remifentanil-propofol Admixture
|