Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

Prolonged Mechanical Ventilation Clinical Trial

Official title:

The Difference and Prognostic Significance of Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05634135
• Other study ID #: 202112183RIND
• Status: Recruiting
• Start date: July 31, 2022
• Est. completion date: July 31, 2024

Study information

• Verified date: July 2023
• Source: National Taiwan University Hospital
• Contact: Jih-Shuin Jerng, MD, PhD
• Phone: +886-2-23123456
• Email: jsjerng[@]ntu.edu.tw
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This project will conduct a series of analysis of physiological and clinical data on tracheostomy patients who receive prolonged mechanical ventilation, hoping to find out the different manifestations of patients through the investigation by a variety of physiologic measurements, so as to understand whether different types of patients phenotype to derive different clinical strategies for liberation of the mechanical ventilator.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: July 31, 2024
• Est. primary completion date: March 31, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• Patients with at least 10 days of mechanical ventilation at the intensive care unit of National Taiwan University Hospital and transferred to the Respiratory Care Center of National Taiwan University Hospital for weaning training

• Patients who have undergone tracheostomy and still have a tracheotomy tube

• Are at least 20 years old

• Stable respiratory condition with inspired oxygen fraction not exceeding 50%

Exclusion Criteria:

• Hemodynamic instability or continuous use of vasopressors

• Pregnancy

Related Conditions & MeSH terms

• Critical Illness
• Prolonged Mechanical Ventilation

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei City

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Liberation from mechanical ventilation at discharge from the weaning unit	At least five consecutive days of free from mechanical ventilation ventilation	Five days