Dopamine D2 Receptors(D2R) Imaging in Prolactinomas

Status Not yet recruiting

Clinical Trial Summary

To study the in vivo expression of dopamine D2 receptors in prolactinoma and the predictive role of dopamine D2 receptors PET-MR imaging in the therapeutic effect of dopamine agonists.

Clinical Trial Description

The dopamine agonist(DA),such as cabergoline(CAB) and bromocriptine(BC), has been used widely in the treatment of prolactinomas, but its clinical use is hampered by intolerance and/or resistant in some patients. It had been showed that DA inhibit prolactin secretion by binding to and activating dopamine D2 receptors.PET-MR combined MR images with PET function images is substantial to evaluate the expression of dopamine D2 receptors.The aim is to study the in vivo expression of dopamine D2 receptors in prolactinoma and the predictive role of dopamine D2 receptors PET-MR imaging in the therapeutic effect of DA. ;

Study Design

Related Conditions & MeSH terms

Prolactinoma

Clinical Trial Details

NCT number	NCT03717454
Study type	Interventional
Source	Ruijin Hospital
Contact	Weiting Gu, MD
Phone	0086-13917778956
Email	nowaiting1221@hotmail.com
Status	Not yet recruiting
Phase	N/A
Start date	December 1, 2018
Completion date	January 31, 2022

View Details

See also
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