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Clinical Trial Summary

This study aims to identify the safety and tolerability of bile acid supplementation in patients with progressive Multiple Sclerosis (MS). Participants will also be assessed for an impact of the bile acid on their immune system and gut microbiome. Half of the participants will receive the bile acid tauroursodeoxycholic acid (TUDCA) and half will receive placebo. The investigators believe participants who take TUDCA will have normalization of blood bile acid levels, a normalization of abnormal immune response and a normalization of the gut microbiome.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03423121
Study type Interventional
Source Johns Hopkins University
Contact
Status Completed
Phase Phase 1/Phase 2
Start date June 19, 2018
Completion date July 5, 2022

See also
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