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Procedural Pain clinical trials

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NCT ID: NCT04571879 Recruiting - Procedural Pain Clinical Trials

Nebulized Lidocaine and Intranasal Midazolam for NGT Insertion in Children

Start date: August 25, 2021
Phase: Phase 3
Study type: Interventional

Nasogastric tube (NGT) is a commonly performed procedure in the Emergency Department. Although it is not a major procedure, it is usually associated with a bad experience and cause discomfort and pain in kids. This randomized controlled double-blinded double-dummy trial aims to investigate the efficacy of local topical anesthetic and/or anxiolysis for pain/anxiety related to NGT insertion. Eligible patients are children with gastroenteritis aged 6 months to 5 years requiring NGT rehydration. The intervention are 3 arms of nebulized lidocaine with midazolam compared to nebulized midazolam alone or placebo. The primary outcome is procedure-related pain assessment using the Face, Legs, Activity, Cry, and Consolability (FLACC) scale during final NGT insertion attempt.

NCT ID: NCT03740607 Recruiting - Procedural Pain Clinical Trials

Virtual Reality for Alleviation of Peripheral IV Placement-Associated Discomfort

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Immersive virtual reality (iVR) has been used successfully to manage pain with distraction. It is a non-invasive treatment modality unassociated with worrisome well-known side effects typically seen when opioids and NSAIDS are used, and has previously been used safely in place of analgesia during dressing changes and burn care. This study investigates whether iVR can be useful as a stand-alone option to manage the pain associated with placement of peripheral intravenous (PIV) catheters in adults.

NCT ID: NCT00908401 Recruiting - Procedural Pain Clinical Trials

Analgesic Effect of Breastmilk for Procedural Pain in Preterm Infants

BMoS
Start date: April 2009
Phase: Phase 3
Study type: Interventional

Hypothesis: Breastmilk has a more powerful analgesic effect than oral sucrose to avoid procedural pain in preterm neonates. The objective is to test this hypothesis in a randomized, controlled study using a standardized and validated pain scale (DAN). The sample size is 21 preterm infants in each two groups. The main end point is a reduction of the risk to have a DAN superior to 1 from 80% with oral sucrose to 40% with breastmilk.