Establishing of an Early Warming System of Premature Ovarian Insufficiency

Status Recruiting

Clinical Trial Summary

Premature ovarian insufficiency (POI) is a clinical syndrome defined by loss of ovarian activity before the age of 40 years. The POI guideline development group of ESHRE recommends the following diagnostic criteria: oligo/ amenorrhea for at least 4 months and an elevated follicle stimulating hormone (FSH) level ＞25 mIU/mL on two occasion ＞4 weeks apart. Some clinicians and researchers proposed that POI was a progressive disease and there were three stages of POI: occult POI, biochemical POI, overt POI. However, there is lack of reliable indicators to assess the different stages of POI. The present study is to explore the change of menstruation condition, basal follicle-stimulating hormone, anti-müllerian hormone and antral follicle count during the development of POI, and whether those marks can assess the different stages of POI.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03518944
Study type	Observational [Patient Registry]
Source	Nanfang Hospital of Southern Medical University
Contact	Shiling Chen, M.D./Ph.D.
Phone	+86-020-62787604
Email	chensl_92@163.com
Status	Recruiting
Phase
Start date	July 1, 2017
Completion date	July 1, 2021

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