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NCT04141865 Clinical Trial

Effect of Xen Implantation on the Aqueous Humor Proteome

Primary Open Angle Glaucoma Clinical Trial

Official title:
Effect of Xen Implantation on the Aqueous Humor Proteome

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT04141865
Other study ID # 2019-006
Secondary ID
Status Terminated
Phase
First received
Last updated
Start date October 24, 2019
Est. completion date February 15, 2022

Study information
Verified date February 2022
Source Price Vision Group
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to determine how the aqueous humor proteome changes after implantation of a Xen microstent for treatment of glaucoma.

Description:

The purpose of this study is to determine how the aqueous humor proteome changes after implantation of a Xen microstent for treatment of glaucoma using liquid chromatography mass spectrometry.

Recruitment information / eligibility
Status Terminated
Enrollment 3
Est. completion date February 15, 2022
Est. primary completion date February 15, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria: - Male or female of any racial or ethnic origin, 18 years or older - Able to provide written informed consent. - Scheduled to undergo Xen implantation for open angle glaucoma or already has an aqueous shunt Exclusion Criteria: - History of conjunctivitis or any ocular infection within the past 3 weeks. - Any active inflammation of the cornea or the anterior chamber (uveitis)

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Xen
Xen microstent implantation
• Aqueous shunt
Aqueous shunt implantation

Locations
Country Name City State
United States Price Vision Group Indianapolis Indiana

Sponsors (1)
Lead Sponsor Collaborator
Price Vision Group

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Aqueous humor proteome The aqueous humor proteome will be assessed with liquid chromotography/mass spectometry (quantitative LC-MS/MS). Change from baseline at 6 months
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