Primary Myelofibrosis Clinical Trial
Official title:
A Phase II Study of Fedratinib and Nivolumab Combination in Patients With Myelofibrosis and Resistance or Suboptimal Response to JAK-inhibitor Treatment
A multicenter, open-label, single arm, phase II study investigating the clinical efficacy of Fedratinib and Nivolumab combination in patients with myelofibrosis and resistance or suboptimal response to JAK-inhibitor treatment
The FRACTION trial will evaluate the clinical efficacy of Fedratinib and Nivolumab combination therapy in patients with primary and secondary myelofibrosis based on the consensus criteria of the International Working Group for Myelofibrosis Research and treatment (IWG-MRT), extended by the criterion RBC-transfusion independence (RBC-TI). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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N/A | |
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||
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Phase 3 | |
| Active, not recruiting |
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N/A | |
| Completed |
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Phase 2 | |
| Completed |
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Phase 2 | |
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|
Phase 1/Phase 2 | |
| Completed |
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Phase 2 | |
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Phase 1 |