Correlation Between Serum Progesterone Level And Primary Dysmenorrhea

Primary Dysmenorrhea Clinical Trial

Official title:

Correlation Between Serum Progesterone Level And Menstrual Symptoms In Young Females With Primary Dysmenorrhea

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06359457
• Other study ID #: P.T.REC/012/005016
• Status: Not yet recruiting
• Start date: May 2024
• Est. completion date: July 2024

Study information

• Verified date: April 2024
• Source: Cairo University
• Contact: MENNAALLAH YOUSEF NASRELDIEN, PhD
• Phone: 01142896492
• Email: mennatullahyousef[@]pt.suez.edu.eg
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study will be conducted to determine Correlation between the levels of serum progesterone and Menstrual Symptoms In Young Females

Description:

One hundred adult females with primary dysmenorrhea will participate in this study. They will be recruited from outpatient clinic of Gynaecological outpatient clinic, faculty of physical therapy, Cairo university, Egypt Many studies reported that primary dysmenorrhea was the result of increased prostaglandin, especially prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) which produced the effect through the cyclooxygenase pathway, and further led to uterine ischemia hypoxia. Nevertheless the relationship between the serum progesterone level and menstrual symptoms was not completely clear. Hence, this study will investigate the association between the serum progesterone level and menstrual symptoms in young female complain of dysmenorrhea and non-dysmenorrhea.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: July 2024
• Est. primary completion date: June 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 17 Years to 24 Years

Eligibility

Inclusion Criteria:

1. One hundreds adult females were suffered from primary dysmenorrhea.

2. Their age was ranged from 17 to 24 years.

3. Their body mass index was ranged from 20 to 25 kg/m2.

Exclusion Criteria:

• Any participant will be excluded from the study if they have:

1. Irregulars or infrequent menstrual cycles.

2. Pacemaker, Myasthenia gravis, hyperthyroidism, active tuberculosis and psychosis.

3. Pelvic pathology.

Related Conditions & MeSH terms

• Dysmenorrhea
• Primary Dysmenorrhea

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Serum progesterone level	Blood samples will be taken by physician for each girl, and will send to laboratory center to measure the progesterone level in the blood. The normal serum progesterone level at 21st day is 4-20ng	Up to 3 months
Primary	Pain intensity	It will be measured by Visual analogue scale. It is a graphic rating scale with numerical values placed equidistantly along the line. The descriptors and numbers help the subject to place her estimate on line in which 0 mean no pain,1 equal mild pain, 2 equal moderate pain, 3 mean sever pain and 4 mean unbearable pain.	Up to 3 months
Primary	Physical and psychological symptoms	It will be measured by menstrual symptoms questionnaire. It was 13 item of 22 item of c-form MSQ (CMSQ) which used to assess the physical and psychological symptoms associated with dysmenorrhea.The score on each item ranged from 1 (never) to 5 (always) with a higher composite score indicating more symptoms	Up to 3 months