Primary Disease Clinical Trial
Official title:
Osteogenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling/Hydroxyapatite Nanoparticles--Comparisons Between Non-viral and Viral Administration in Tissue Engineered Bone Regeneration
The first year purpose:
The best concentration of canonical Wnt3a will be investigated in promoting the
osteoblastogenesis of human mesenchymal stem cells.
Our previous work is investigating the viral (Adv-BMP-2) administration for the development
of a model to generate bones for possible use in clinical settings; the non-viral and viral
administrations will be compared for best osteogenesis effects.
The first year purpose:
The best concentration of canonical Wnt3a will be investigated in promoting the
osteoblastogenesis of human mesenchymal stem cells.
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N/A
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