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Study Evaluating the Safety and Tolerability of RCT1100 in Healthy and PCD Subjects

Primary Ciliary Dyskinesia Clinical Trial

Official title:
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study, in Healthy Adult Participants and Open-Label Single Ascending Dose Study in Adults With Primary Ciliary Dyskinesia Caused by Pathogenic Mutations in the DNAI1 Gene to Evaluate the Safety and Tolerability of RCT1100

Clinical Trial Summary

This is the first-in-human study with RCT1100 and is designed to provide initial safety and tolerability data for future clinical studies.

Clinical Trial Description

The primary objective of this study is to assess the safety and tolerability of a single ascending dose of inhaled RCT1100 administered via nebulizer to healthy participants and patients with Primary Ciliary Dyskinesia caused by a pathogenic mutation in the DNAI1 Gene. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05737485
Study type Interventional
Source ReCode Therapeutics
Contact Priya Ryali, MBA
Phone 650-629-7900
Email clinicaltrials@recodetx.com
Status Recruiting
Phase Phase 1
Start date February 18, 2023
Completion date December 21, 2024
View Details
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