Genetic Epidemiology of Primary Biliary Cirrhosis (PBC)

Status Active, not recruiting

Clinical Trial Summary

Primary Biliary Cirrhosis (PBC) is a progressive liver disorder of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PBC. This study is being done to investigate whether genes make people more likely to develop PBC. Discovery of these proposed genes will help us better understand how PBC developes, and subsequently, to apply new approaches for its prevention, diagnosis and treatment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01161953
Study type	Observational
Source	Mayo Clinic
Contact
Status	Active, not recruiting
Phase
Start date	March 2002
Completion date	December 2050

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT04526665` - Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)	Phase 3
Recruiting	`NCT02931513` - sCD163 in PBC Patients - Assessment of Treatment Response
Active, not recruiting	`NCT02924701` - sCD163 in PBC Patients - Assessment of Disease Severity and Prognosis
Completed	`NCT02659696` - Nalfurafine Hydrochloride for Pruritus in Patients With Primary Biliary Cholangitis
Completed	`NCT02078882` - Study of Abatacept (Orencia) to Treat Primary Biliary Cirrhosis	Phase 4
Completed	`NCT01603199` - High-protein High-fiber Diet in Patients With Primary Biliary Cirrhosis	N/A
Completed	`NCT01389973` - A Study of Efficacy and Safety of Ustekinumab in Patients With Primary Biliary Cirrhosis (PBC) Who Had an Inadequate Response to Ursodeoxycholic Acid	Phase 2
Completed	`NCT01857284` - Safety and Efficacy of Tauroursodeoxycholic Acid Versus Ursofalk in the Treatment of Adult Primary Biliary Cirrhosis	Phase 3
Completed	`NCT05374200` - Mind-body Wellness Intervention in Primary Biliary Cholangitis (PBC)	N/A
Recruiting	`NCT02937012` - Use of Bezafibrate in Patients With Primary Biliary Cirrhosis to Archive Complete Biochemical Response in Non-responders	Phase 3
Completed	`NCT02376335` - B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis	Phase 2
Recruiting	`NCT01662973` - Umbilical Cord Mesenchymal Stem Cells for Patients With Primary Biliary Cirrhosis	Phase 1/Phase 2
Active, not recruiting	`NCT04751188` - A Study to Assess Efficacy and Safety of Bezafibrate in Patients With Primary Biliary Cholangitis	Phase 3
Recruiting	`NCT04514965` - Bezafibrate in Patients With Primary Biliary Cholangitis (PBC)
Recruiting	`NCT03668145` - Mesenchymal Stem Cell Transplantation for Refractory Primary Biliary Cholangitis	N/A
Completed	`NCT02955602` - Seladelpar (MBX-8025) in Subjects With Primary Biliary Cholangitis (PBC)	Phase 2
Completed	`NCT02557360` - Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis	Phase 4
Recruiting	`NCT01440309` - Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Refractory Primary Biliary Cirrhosis	Phase 1
Completed	`NCT01249092` - Pentoxifylline for Primary Biliary Cirrhosis	Phase 2
Completed	`NCT01510860` - Ursofalk Tablets (500 mg) Versus Ursofalk Capsules (250 mg) in the Treatment of Primary Biliary Cirrhosis	Phase 4