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Presbyopia clinical trials

View clinical trials related to Presbyopia.

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NCT ID: NCT05294328 Completed - Presbyopia Clinical Trials

Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia

Start date: May 5, 2022
Phase: Phase 2
Study type: Interventional

To evaluate the safety and effectiveness of Aceclidine/Brimonidine (LNZ101) compared with Aceclidine (LNZ100) and vehicle in the treatment of Presbyopia.

NCT ID: NCT05270863 Completed - Presbyopia Clinical Trials

Safety and Efficacy Study BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic or Pseudophakic Presbyopia

Start date: March 30, 2022
Phase: Phase 3
Study type: Interventional

Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia

NCT ID: NCT05252871 Completed - Presbyopia Clinical Trials

Assessment of Three Basic Progressive Lens Designs

Start date: December 9, 2021
Phase: N/A
Study type: Interventional

This clinical trial investigates the differences between three different progressive addition lens designs. It is a non-invasive double-masked randomized clinical investigation. For this study, 80 participants will be recruited.

NCT ID: NCT05191329 Completed - Clinical trials for Patient Satisfaction

Impact of Personality on Satisfaction Following Presbyopic Correction

Start date: August 28, 2021
Phase:
Study type: Observational [Patient Registry]

Primary objective of this study is the exploration of the impact of personality type, social roles and working mandates οn the visual capacity and satisfaction of patients that underwent pseudophakic presbyopic correction.

NCT ID: NCT05124275 Completed - Presbyopia Clinical Trials

Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia

Start date: January 3, 2022
Phase: Phase 2
Study type: Interventional

This is a Multicenter, Randomized, Double-Masked Placebo-Controlled, Parallel Group Phase 2 Trial Evaluating the Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia.

NCT ID: NCT05114486 Completed - Presbyopia Clinical Trials

Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults

VISION-2
Start date: November 3, 2021
Phase: Phase 3
Study type: Interventional

Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 2 treatment visits. At each treatment visit, 1 of the 2 study treatments is self-administered to both eyes. Afterwards, efficacy and safety assessments are performed over a 3-hour period.

NCT ID: NCT05069415 Completed - Cataract Clinical Trials

Monofocal IOL Visual Outcomes When Targeting Mini Monovision

Start date: October 4, 2021
Phase: N/A
Study type: Interventional

This study is a 3-month, prospective, up to 2 center, bilateral, randomized subject masked clinical evaluation of a monofocal intraocular lens (IOL) when both eyes are targeted for emmetropia and when the non-dominant eye is targeted for mini monovision (-0.75 D) in patients with or without astigmatism undergoing routine cataract surgery.

NCT ID: NCT05006898 Completed - Presbyopia Clinical Trials

Compound to Control Presbyopia Symptoms

Start date: June 1, 2020
Phase: Phase 1
Study type: Interventional

Low dose compose to control presbyopia symptoms

NCT ID: NCT05005624 Completed - Presbyopia Clinical Trials

Validation of an Activities-of-daily-living Framework at Different Light Conditions

Start date: July 1, 2020
Phase:
Study type: Observational

Primary objective of this study is the construction and validation of an experimental environment for the simulation of a variety of near- and intermediate-vision activities of daily living (ADLs) in different combinations of light temperature and light intensity.

NCT ID: NCT04983589 Completed - Presbyopia Clinical Trials

A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-190584 in Both Eyes Twice Daily

Virgo
Start date: September 2, 2021
Phase: Phase 3
Study type: Interventional

Currently available treatments for presbyopia (old eye) include nonsurgical options (spectacles or contact lenses) and surgical options, however, each has its own risks and limitations. The purpose of this study is to evaluate how effective AGN-190584 is in treating presbyopia compared to vehicle (placebo). AGN-190584 is an investigational drug being developed for the treatment of presbyopia. Participants are placed in 1 of 2 groups, called treatment arms. Each group receives a different treatment. There is a 1 in 2 chance that participants will be assigned to vehicle. Around 200 participants age 40-55 years with a diagnosis of presbyopia will be enrolled in the study in approximately 20 sites in the United States. Participants will receive AGN-190584 or vehicle in each eye twice daily for 14 days. There may be additional procedures for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a doctor's office. The effect of the treatment will be checked by medical assessments, vision/eye tests, checking for side effects and completing questionnaires.