Human Amniotic Epithelial Cells Treatment for Ovarian Insufficiency

Status Not yet recruiting

Clinical Trial Summary

This project will investigate the safety and effectiveness of human amniotic epithelial cells in primary ovarian insufficiency patients and provide a new cell therapy against infertility.

Clinical Trial Description

Premature ovarian insufficiency (POI) refers to women before the 40 years of age who suffer clinical manifestations of ovarian recession. Now, there is no exact and effective treatment to restore ovarian function. Human amniotic Epithelial cells (hAECs) are derived from human amniotic epithelium. hAECs retain the characteristics of embryonic stem cells, as well as a strong differentiation potential and plasticity. Experiments show that the fertility of mice is significantly improved after amniotic epithelial cells implantation. In order to further study the role of hAECs in POI treatment, this project will conduct minimally invasive implantation with hAECs in 20 cases of POI patients, and evaluate the changes of ovarian function and the safety of hAECs implantation. hAECs is prepared by Chongqing iCELL Biotechnology Co.,Ltd., which is a subsidiary of Shanghai iCELL Biotechnology Co.,Ltd. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03207412
Study type	Interventional
Source	The Second Affiliated Hospital of Chongqing Medical University
Contact	Chanyu Zhang
Phone	86-23-63693296
Email	1317954623@qq.com
Status	Not yet recruiting
Phase	N/A
Start date	December 22, 2017
Completion date	December 31, 2019

View Details

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