Premature Birth Clinical Trial
Official title:
Neuroendocrine Mechanisms of Growth and Body Composition in Preterm and Term Infants
The purpose of this study is to test the feasibility of measuring body composition by air displacement plethysmography (ADP) in rapidly growing, medically stable late gestation [32-35 weeks post-menstrual age (PMA)] premature infants.
1. To assess the feasibility of measuring body fat deposition by ADP in medically stable
late gestation (32-35 weeks), premature infants during a period of rapid postnatal
growth.
2. To test the relationship between %BF by ADP to %BF by DXA, as well as characterize the
relationship between these fat measures with bone measures by quantitative ultrasound
and serum levels of insulin, IGF-1, IGF binding proteins, adiponectin and leptin.
3. To perform inter- and intra-rater testing of anthropometric, ultrasound, and ADP
measurements.
4. Compare growth, body composition and bone strength between infants born preterm to
infants born full term.
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