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Pregnancy, Prolonged clinical trials

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NCT ID: NCT02932319 Terminated - Prolonged Pregnancy Clinical Trials

Outpatient Foley Catheter for Induction of Labor in Nulliparous for Prolonged Pregnancy

FOLOUT
Start date: March 31, 2017
Phase: N/A
Study type: Interventional

15 to 20 % of nulliparous needs an induction at term. None study has evaluated Foley catheter induction at home versus expectative in this population

NCT ID: NCT02916082 Completed - Clinical trials for Pregnancy, Prolonged

Cervical Length Pre-induction as a Tool to Predict Vaginal Birth

Start date: November 2015
Phase: N/A
Study type: Observational

To evaluate the value of measuring cervical length as a predictor of vaginal birth after induction of labor with prostaglandins in pregnancies with 41 weeks of gestation.

NCT ID: NCT02907060 Completed - Prolonged Pregnancy Clinical Trials

Mechanical cervicAl ripeninG for Women With PrOlongedPregnancies

Start date: January 27, 2017
Phase: Phase 3
Study type: Interventional

A pregnancy is considered ''prolonged'' from 41 weeks of gestation. Prolonged Pregnancies (PP) are associated with increased maternal morbidity: emergency caesarean, 3rd and 4th degree perineal lesions and postpartum haemorrhage. Foetuses are at increased risk of oligohydramnios, meconium-staining and Fetal Heart Rate (FHR) anomalies. Around 15% of all pregnancies are prolonged. A Cochrane review on induction of labour showed that a policy of labour induction at or beyond 41 weeks was associated with significantly fewer perinatal deaths. Thus the French College of Obstetricians and Gynaecologists stated, "induction of labour can be proposed to patients between 41+0 and 41+6 weeks of gestation". In cases where labour is induced and cervix is unfavourable, cervical ripening is advised. Methods of cervical ripening include pharmacological (prostaglandins) and mechanical (Foley catheter or trans-cervical double balloon) methods. Those two methods were compared in the PROBAAT trial among women with term pregnancies (beyond 37+0). The rates of caesarean section with these two strategies were identical, however uterine hyper stimulation with FHR anomalies occurred less when cervical ripening was mechanical. Considering pharmacological cervical ripening is associated with more uterine hyper stimulation and more FHR anomalies, it may not be the most appropriate in cases of fragile foetuses that include cases of prolonged pregnancies. Considering prolonged pregnancies are associated with a risk of FHR anomalies and that cervical ripening with a pharmacological method is another factor which increases this risk: women with prolonged pregnancies could benefit from a more "gentle" cervical ripening. At present, no particular method is recommended in cases of cervical ripening and prolonged pregnancies. We hypothesise that, in cases of prolonged pregnancies, mechanical cervical ripening, with less uterine hyperstimulation and fewer FHR anomalies, could be more appropriate and could reduce the rate of caesarean section for suspicion of fetal distress.

NCT ID: NCT02793609 Completed - Prolonged Pregnancy Clinical Trials

Outpatient Versus Inpatient Balloon Catheter Induction of Labor

Start date: June 1, 2016
Phase: N/A
Study type: Interventional

Randomized trial comparing double balloon catheter for induction of labor between in- and outpatient groups.Investigators assess feasibility, clinical effectiveness and patient acceptability of outpatient versus inpatient catheter for induction of labor.

NCT ID: NCT02680093 Not yet recruiting - Clinical trials for Pregnancy, Prolonged

Birth Rate in Conservative Monitoring of Pregnancy Beyond the Date of Birth.

Start date: February 2016
Phase: N/A
Study type: Observational

Pregnant Women beyond the date of birth. will be followed while coming to routine monitoring. physiological parameter of cervical length will be measured as the differential predictor to determine their due date. the cervical length will be measured as part of routine gynecologic examination to women who come for routine over due date follow up. additional medical data will be collected from the patient medical record.- demographic data, and all the routine prenatal medical care the women will receive up to the delivery.and delivery outcomes.

NCT ID: NCT02392988 Not yet recruiting - Clinical trials for Post-term Pregnancy (40 to 42 Weeks Gestation)

Does Acupuncture Therapy Reduce the Need for Labor Induction After Postdate (Week 41)

Start date: May 2015
Phase: N/A
Study type: Interventional

In recent years, it is accepted to induce birth at week 41 in order to reduce the risk in surplus pregnancies. It was found that after 41 weeks, there is a significant increase in pregnancy complications including meconium liquor, shoulder dystocia and fetal death in uterus. Induction at 41 weeks was found to reduce the risk of complications described above, without taking the risk of cesarean section and, therefore, the recommendation of the Israel Society of Maternal Fetal Medicine, is to induce birth for women who completed 41 weeks of pregnancy. Induction is performed mechanically by entering a balloon to the cervix or by medicated prostaglandins and later, intravenous Pitocin to most women. The process takes two to three days with about 60-70% success rate. In recent years there has been a growing awareness to use natural methods to start labor. Many women tend to turn to natural medicine in order to reduce the need for conventional drugs to start labor. Given the lack of research on the issue and considering the rising demand of the involvement of alternative medicine in labor induction process, the investigators decided to carry out research on this subject.

NCT ID: NCT02255903 Recruiting - Clinical trials for Pregnancy, Prolonged

Middle Cerebral To Umbilical Artery Doppler Ratio And Amniotic Fluid Volume Measurement In Post-date Pregnancies in King Khalid Military Central City

Start date: February 2022
Phase:
Study type: Observational

The aim of this study is to assess the values of MCA PI / UA PI and MCA RI / UA RI ratios and amniotic fluid volume in predicting the adverse perinatal fetal outcome in uncomplicated postdate pregnancy

NCT ID: NCT01542151 Completed - Clinical trials for Pregnancy, Prolonged

Effects of Sleep, Fatigue, and Timing of Post-dates Inductions Among Nulliparas

Start date: October 2011
Phase: N/A
Study type: Interventional

This randomized clinical trial will examine if there are any differences between post-dates inductions (inductions after 40 weeks of pregnancy) begun in the morning compared to the evening for first-time mothers. Sleep and fatigue measures will be measured to see if they differ by time of induction. Other measures will include the rate of births within 24 hours of admission, length of labor, use of labor analgesics, and method of delivery.

NCT ID: NCT01429974 Terminated - Meconium Clinical Trials

Detection of Meconium in Amniotic Fluid in Post Term Pregnancies

Start date: September 2011
Phase: N/A
Study type: Observational

Meconium constitutes the bowel contents of the fetus and is normally expelled only after birth. However, it may be secreted into the amniotic fluid of 20% of all fetuses. Meconium Stained Amniotic Fluid had been recognized from ancient times as an obstetric hazard which complicates delivery and is associated with increased newborn morbidity and mortality. At present there is no viable diagnostic test for Meconium prior to the onset of labor and the rupture of membranes. The system developed for the detection of Meconium, based on recognizing a characteristic fluoroscopic spectral pattern emitted by Meconium under light excitation at a specific wavelength. The diagnostic test being developed does not require penetration into the amniotic sac and is safe, painless and simple to perform.

NCT ID: NCT01140971 Completed - Oligohydramnios Clinical Trials

Foley Catheter Versus Vaginal Misoprostol for Cervical Ripening and Induction of Labor

Start date: January 2006
Phase: N/A
Study type: Interventional

PURPOSE: The purpose of this study is to determine the effectiveness of balloon dilatation (Foley) with vaginal misoprostol for cervical ripening and induction of labor. METHOD: a randomized clinical assay has been performed with 160 women with indication of induction of labor, randomly divided in two groups, 80 for Foley catheter and 80 for misoprostol.